The RDC is jointly headed by a Chairperson and a Co-Chairperson appointed by the President of the Philippines. If the Chairperson comes from the government, the Co-Chairperson must come from the private sector, or vice-versa. Only elective officials are appointed as Chair or Co-Chairperson.
The NEDA Regional Director is the ex-officio Vice-Chairperson of the RDC, while the NEDA Assistant Regional Director is the ex-officio Secretary.
The same officials serve as the ex-officio Chairperson, Co-Chairperson, Vice-Chairperson, and Secretary of the RDC Executive and Advisory Committees.
The terms of office of the Chairperson, Co-Chairperson and the PSRs coincide with the regular term of local elective officials. This prescribed term of office is without prejudice to reappointment.
|1995-1998||Ma. Angelica Rosedell Amante (Governor, Agusan del Norte)||Felix Villacastin||Jose Mazo||Johnny Lim|
|1998-2001||Valentina Plaza (Governor, Agusan del Sur)||Engr. Epimaco Galero Jr.||Jose Mazo||Johnny Lim|
|2001-2004||Lyndon Barbers (Governor, Surigao del Norte)||None||Carmencita Cochingco|
|2004-2007||Democrito Plaza II (Mayor, Butuan City)||Engr. Leonel Santos||Carmencita Cochingco|
|2010-2013||Sol Matugas (Governor, Surigao del Norte)||Marlon Advincula (Private Sector Representative)||Carmencita Cochingco||Mylah Faye Aurora Carino (2012-2013)|
|2013-2016||Sol Matugas (Governor, Surigao del Norte)||Mylah Faye Aurora Carino||Roy Kantuna (2015-2016)|
|2016-2019||Sol Matugas (Governor, Surigao del Norte)||TBA||Mylah Faye Aurora Carino||Roy Kantuna|